According to findings by Friedmann and co-workers (1993), low doses of light intensify the formation of a transmembrane electrochemical proton gradient in mitochondria.
The process happens upon absorption of mitochondrial chromophores such as cytochromes, which are followed by calcium release from mitochondria into cytoplasm by a calcium/hydrogen antiport system and subsequently triggers mitosis and cell proliferation.
Low light energy inserted into cells proliferates and stimulates collagen production and induces collagen and elastic tissue synthesis.
Lubart and colleagues (1993) investigated the effect of light intensities on mammalian cells, they found that the induction of fibroblast proliferation at a constant dose depends on the applied intensity in a non linear manner. Moreover, they demonstrated distinct combinations of dose and intensity at which the induction of cell proliferation was maximal in a wavelength dependent manner. Van Breughel (1992) irradiated fibroblast cultures at a constant dose varying intensities and exposure time. Results show that the proliferation and collagen production could be only stimulated with medium intensities and exposure times.
The Crystal 512 and Record 618 uses specific dose, intensity and wavelengths that enable it to stimulate the cells to produce more collagen and thus rejuvenating the skin.